2,3-dihydro-3-oxo-4H-pyrido[3,2-b]-1,4-oxazine
2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one
CAS: 20348-09-8
Molecular Formula: C7H6N2O2
2,3-dihydro-3-oxo-4H-pyrido[3,2-b]-1,4-oxazine - Names and Identifiers
| Name | 2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one |
| Synonyms | TIMTEC-BB SBB006815 LABOTEST-BB LT00451615 4H-Pyrido[3,2-b][1,4]oxazin-3-one 4H-pyrido[2,3-e][1,4]oxazin-3-one 2H-Pyrido[3,2-b]-1,4-oxazin-3(4H)-one 2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one 2H-Pyrido[3,2-b][1,4]oxazin-3(4H)-one 2H-PYRIDO[3,2-B]-1,4-OXAZIN-3(4H)-ONE 2,3-dihydro-3-oxo-4H-pyrido[3,2-b]-1,4-oxazine 3,4-Dihydro-2H-pyrido[3,2-b]-1,4-oxazine-3-one |
| CAS | 20348-09-8 |
| EINECS | 243-751-1 |
| InChI | InChI=1/C7H6N2O2/c10-6-4-11-5-2-1-3-8-7(5)9-6/h1-3H,4H2,(H,8,9,10) |
2,3-dihydro-3-oxo-4H-pyrido[3,2-b]-1,4-oxazine - Physico-chemical Properties
| Molecular Formula | C7H6N2O2 |
| Molar Mass | 150.13 |
| Density | 1.327±0.06 g/cm3(Predicted) |
| Melting Point | 204-206°C(lit.) |
| Boling Point | 384.2±37.0 °C(Predicted) |
| Flash Point | 186.133°C |
| Vapor Presure | 0mmHg at 25°C |
| BRN | 1074010 |
| pKa | 11.06±0.20(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.568 |
2,3-dihydro-3-oxo-4H-pyrido[3,2-b]-1,4-oxazine - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection |
| WGK Germany | 3 |
| Hazard Class | IRRITANT |
2,3-dihydro-3-oxo-4H-pyrido[3,2-b]-1,4-oxazine - Reference Information
| application | pyridine oxazine is a kind of secondary metabolites widely existing in gramineous plants. it has broad-spectrum disease resistance and insect resistance, can act on a variety of crop diseases and insect pests, and is also a resistance index for crop breeding. This kind of chemical substance is represented by Dingbu, which is an important compound for studying the relationship between insects and plants. |
| preparation | due to the special biological activity of pyridine oxazine compounds, the synthesis of such compounds has been widely concerned. the commonly used method for synthesizing pyridine [3,2-b][1,4] oxazine compounds in the literature is prepared by Mannich reaction with phenol, primary amine and aldehyde as raw materials. Another more important method is to use o-aminomethylphenol and aldehydes or ketones to shrink into rings under the catalysis of SnCl4, Me,SiCl, etc. In this paper, the target compound 2H-pyridine [3,2-b][1,4] oxazin-3 (4H)-one [1] was prepared by ring-closing reaction with 2-amino-3-hydroxypyridine and chloroacetic acid as starting materials. The synthesis reaction formula of 2H-pyridino [3,2-b][1,4] oxazine -3(4H)-one is as follows: |
Last Update：2024-04-09 18:58:34
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